Scientists tested a toad venom psychedelic on treatment-resistant depression. Here's what happened

A phase 2b clinical trial involving 193 participants with treatment-resistant depression found that a single dose of mebufotenin, a synthetic compound derived from Sonoran Desert toad venom, was safe and effective. The nasal spray formulation produced rapid antidepressant effects, with most patients ready for discharge within two hours. Researchers published the results in the Journal of the American Medical Association, suggesting the drug could offer a faster alternative to existing treatments.

Source: Scientists tested a toad venom psychedelic on treatment-resistant depression. Here's what happened — ScienceAlert

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Topics: psychedelics · depression · mentalhealth · toadvenom · 5meodmt · science · clinicaltrial