A 1970s lab compound just made mice lose 18% of their body weight while eating the same — and no one's sure why.

Experimental Drug Makes Obese Mice Burn Fat Without Losing Muscle – Or Eating Less

An experimental compound called TOFA, given orally to obese mice for four weeks, produced an 18% average weight loss without changing food intake or activity. It appears to both reduce fat production and increase fat burning, though the exact mechanism remains unclear. The results suggest a potential new approach to obesity treatment that targets energy expenditure rather than appetite.

Source: Experimental Drug Makes Obese Mice Burn Fat Without Losing Muscle – Or Eating Less — ScienceAlert

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